If you're pretty sure you have bed bugs in your car there are a few things you should do : Inspect your car thoroughly. You should be able to locate bed bugs with a flashlight, particularly in upholstery or carpeted floor mats. Make sure you check the corners of your car and the center console, as these are common hiding areas.
Yes, bed bugs can infest leather furniture/items if that is what you mean. They don't burrow or penetrate materials so they won't actually live inside of the leather. They could nest underneath of the leather if there are voids allowing access.
While bed bugs can live in leather, suede, or vinyl, they are less likely to hide in that kind of material. Since leather is not very climber-friendly, bed bugs will usually opt for a hiding place that is easier to move to and from.
The most common insects that invade cars are of course cockroaches and ants but wasps can build nests and a number of so called "stored product" pests like carpet beetles are common as well. It is, however, very unlikely that bed bugs would infest cars unless someone is actually living and sleeping in the vehicle.
I Have Bed Bugs, Now What? Contact a professional: The complete elimination of bed bugs requires highly trained and licensed individuals knowledgeable in bed bug biology, behavior, and the proper use of pesticides. There is little chance that you will be able to eliminate the problem on your own.
If your car has been infested with bed bugs, they must have come from somewhere. As they can travel on clothes and luggage, make sure to give those a full cleaning. If you check your home and office with the bed bug inspection methods described above and find the critters lurking, it's time to clean those areas, too.