A bed bug's mouthparts can't penetrate most clothing, but that doesn't make clothes a good option for preventing bites if you have an infestation. Not only can they crawl under clothes, but they are happy to bite any exposed area of skin, including the face and neck.
The most likely way that bed bugs get into clothes is in your luggage. If you're staying at a hotel, or even transporting your suitcase or bag in an infested vehicle, the bugs may crawl inside. To prevent this from happening, don't lay your luggage on the bed when you arrive in a hotel room.
Duration bed bugs stay in your clothes. Bed bugs can live in your clothes for a year or more. The bed bugs can live in your clothes as long as it is a good hiding place for them. Bed bugs can live for a year without having to feed on your blood and that confirms why they can go for a year or more unnoticed.
Bed bugs do like to hide in piles of laundry and (surprise) your bed, bed-skirt, and box spring. They will make it into couch cushions and blankets, and whatever else they can. More often than not, though, they are coming in through a hole, opening, or crack somewhere.
Washing will kill some of the bed bugs, but it is the heat of drying that will kill any remaining bed bugs. With a few common-sense practices, you can easily disinfest clothes and ensure these items do not become bed bug hiding places as you remove bed bugs from the rest of your home.
Bed bugs can hitch a ride on clothing that you wear, but only on your outfit, not directly on your body. If you suspect that there are bed bugs on some of your clothes, remove them in a place with a non-carpeted floor and put them into a plastic bag.